Drug

Semalgid™ - semaglutide.

The active ingredient Semalgid™ is semaglutide, an analogue of glucagon-like peptide-1, which is produced in the human body and regulates insulin secretion.

Semaglutide reduces total body weight and adipose tissue mass by reducing energy intake. This mechanism involves a general decrease in appetite, including increased satiety signals and decreased hunger signals, as well as improved control of food intake and decreased food cravings. In addition, semaglutide reduces the preference for high-fat foods.
Usage

Use of the drug

Semalgid™ reduces blood glucose levels in adults with type 2 diabetes (plasma glucose and glycated hemoglobin (HbA1c)).

Semalgid™ suppresses appetite and reduces calorie intake by 18-35% throughout the day. Semalgid™ reduces body weight mainly by reducing the mass of adipose tissue.

Semalgid™ reduces the risk of serious cardiovascular events.

Semalgid™ lowers triglyceride and cholesterol concentrations and reduces systolic blood pressure.
ANSWERS ON QUESTIONS

Isn't this insulin?

Semalgid™ is not insulin, it is a different class of drugs. Moreover, its mechanism of action is aimed at reducing insulin resistance, i.e. normalizing the sensitivity of human body cells to their endogenous insulin, and semaglutide improves the functioning of pancreatic cells. Those. The action of the drug is aimed at normalizing the body’s own functioning, so that it allows you to take type 2 diabetes under control, even “roll back the disease,” improve its prognosis, and significantly delay the need for insulin replacement therapy.

ANSWERS ON QUESTIONS

Will I have to inject Semalgid™ for the rest of my life?

For type 2 diabetes mellitus, Semalgid™ is indicated for a long time, because It helps reduce insulin resistance and has a beneficial effect not only on the cells of the pancreas that produce insulin, but also helps normalize systolic blood pressure, improve lipid profile and much more. In the case of using Semalgid™ for the purpose of losing weight, the duration of the course depends on many factors: how long a person has been living with increased body weight, how much food he consumed per day in terms of volume and calories before starting therapy, how quickly he lost weight, whether he plays sports, duration sleep and much more. The optimal weight loss for the body is on average 5% over 3 months. Firstly, a more intense loss is stress for the body, and secondly, with rapid weight loss, a factor such as “obesogenic memory” is activated - this is the re-gain of body weight after its loss against the background of successful obesity therapy. By decision of the medical commission, Semalgid™ can be prescribed to help the body develop the habit of eating little, which contributes to gradual weight loss. The duration of the course in this case, as a rule, ranges from 6 months to 2 years.

ANSWERS ON QUESTIONS

Is Semalgid™ as effective as Ozempic™?

We conducted clinical studies of the drug Semalgid™, which proved complete identity to the drug Ozempic™.

ANSWERS ON QUESTIONS

Does the price of Semalgid™ correspond to the price of the original drug?

The state strictly regulates the cost of vital drugs, and Semalgid™ is one of them. Therefore, the price of drug registration according to the legislation of the Russian Federation should be lower than the price of the original drug - Ozempic™. In pharmacies the price will vary from 6,500 rubles. up to 7,800 rub. depending on the region.

PRODUCT

Release form of the drug

Along with the syringe in the package you will find 8 disposable needles for the convenience of selecting an individual dose.

The package contains a ready-made device with 10 ml of the drug. The syringe pen with a dispenser allows you to administer doses of 0.25 ml, 0.5 ml and 1 ml.

Story

Brief history of the drug

  • Semaglutide was developed by Novo Nordisk as a treatment for diabetes mellitus (trademark Ozempic).
  • A group of scientists from the University of Leeds announced the possible effectiveness of semaglutide in the treatment of obesity.
  • The drug is approved for market in the European Union and registered in Russia.
  • Semaglutide is included in the Russian “List of Vital and Essential Medicines” by the Ministry of Health of the Russian Federation.
  • Novo Nordisk has stopped supplying Ozempic to Russia.
  • The NGPharma company produces an analogue of the drug Ozempic under the Semalgid brand.